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Crosstalk between mitochondrial biogenesis and mitophagy to maintain mitochondrial homeostasis

11 Oct 2023

Abstract excerpt

Mitochondrial mass and quality are tightly regulated by two essential and opposing mechanisms, mitochondrial biogenesis (mitobiogenesis) and mitophagy, in response to cellular energy needs and other cellular and environmental cues. Great strides have been made to uncover key regulators of these complex processes. Emerging evidence has shown that there exists a tight coordination between mitophagy and...

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Share to Autophagy in Disease and Therapy
Share to Epigenetics and DNA Methylation
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PMID: 37821940
DOI: 10.1186/s12929-023-00975-7

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