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Article

FTO variation and early frontostriatal brain development in children.

Obesity (Silver Spring, Md.) - 1 Jan 2024

Thapaliya Gita, Kundu Poorbita, Jansen Elena, Naymik Marcus A, Lee Richard, Bruchhage Muriel Marisa Katharina, D'Sa Viren, Huentelman Matthew J, Lewis Candace R, Müller Hans-Georg, Deoni Sean C L, Carnell Susan

Abstract excerpt

OBJECTIVE: Common obesity-associated genetic variants at the fat mass and obesity-associated (FTO) locus have been associated with appetitive behaviors and altered structure and function of frontostriatal brain regions. The authors aimed to investigate the influence of FTO variation on frontostriatal appetite circuits in early life. METHODS: Data were drawn from RESONANCE, a longitudinal study of early brain...

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Share to Alpha-Ketoglutarate-Dependent Dioxygenase FTO
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 37817330
DOI: 10.1002/oby.23926
PMCID: PMC10840826

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