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Type V Protein Secretion Pathway: the Autotransporter Story

1 Dec 2004

Abstract excerpt

Gram-negative bacteria possess an outer membrane layer which constrains uptake and secretion of solutes and polypeptides. To overcome this barrier, bacteria have developed several systems for protein secretion. The type V secretion pathway encompasses the autotransporter proteins, the two-partner secretion system, and the recently described type Vc or AT-2 family of proteins. Since its discovery in the late...

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PMID: 15590781
DOI: 10.1128/mmbr.68.4.692-744.2004

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