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Article

Proteogenomic profiling predicts outcomes of adjuvant chemotherapy in extrahepatic cholangiocarcinoma.

Journal of hepatology - 1 Jan 2026

Jeong Hyehyun, Oh Ji-Hye, Ahn Hee-Sung, Ryoo Baek-Yeol, Kim Kyu-Pyo, Jeong Jae Ho, Park Inkeun, Hwang Dae Wook, Lee Jae Hoon, Song Ki Byung, Lee Woohyung, Kim Ki-Hun, Moon Deog-Bog, Song Gi Won, Jung Dong-Hwan, Hong Seung-Mo, Park Chae Won, Baek In-Pyo, Cho You Sook, Kim Kyunggon, Sung Chang Ohk, Yoo Changhoon

Abstract excerpt

BACKGROUND & AIMS: Cholangiocarcinoma is a heterogeneous disease, and its molecular characteristics and biomarkers are not yet fully understood. We performed comprehensive proteogenomic analyses to investigate the molecular landscape of extrahepatic cholangiocarcinoma (EH-CCA). METHODS: Prespecified exploratory analyses were conducted within the STAMP trial - a randomized phase II trial of adjuvant capecitabine...

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Share to Bile Duct Neoplasms
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 40803577
DOI: 10.1016/j.jhep.2025.07.031

Genes

IMPACT
KRAS
PIK3CA
SMAD4
TP53

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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