Article
Deleterious and ethnic-related BRCA1/2 mutations in tissue and blood of Egyptian colorectal cancer patients and its correlation with human papillomavirus.
Clinical and experimental medicine - 1 Dec 2023
Youssef Amira Salah El-Din, Zekri Abdel Rahman N, Mohanad Marwa, Loutfy Samah A, Abdel Fattah Nasra F, Elberry Mostafa H, El Leithy Asmaa A, El-Touny Ahmed, Rabie Ahmed Samy, Shalaby Mohamed, Hanafy Ayman, Lotfy Mai M, El-Sisi Enas R, El-Sayyad Gharieb S, Nassar Auhood
Abstract excerpt
This study aimed to identify BRCA1/2 mutational patterns in the tissue and blood of Egyptian colorectal cancer (CRC) patients and to study the possible correlation of this mutational pattern with Human papillomavirus (HPV) infection. Eighty-two colonoscopic biopsies and forty-six blood samples were collected from Egyptian CRC patients, as well as blood samples of age and sex-matched healthy controls (n = 43) were...
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