Article
Association of MIF-173G/C, IL-4 VNTR, and IL-1RA VNTR variants with FMF-related amyloidosis in a Turkish cohort.
Journal of investigative medicine : the official publication of the American Federation for Clinical Research - 1 Jan 2024
Yigit Serbulent, Nursal Ayse Feyda, Keskin Adem, Kaya Suheyla, Kuruca Nilufer, Sezer Ozlem
Abstract excerpt
The most important complication of familial Mediterranean fever (FMF) is secondary amyloidosis. The aim of this study is to investigate the risk of developing FMF-related amyloidosis with macrophage migration inhibitory factor (MIF), interleukin 4 (IL-4), and IL-1 receptor antagonist (IL-1RA) variants. This study included 62 FMF patients with amyloidosis, 110 FMF patients without amyloidosis, and 120 controls....
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