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Human obstructive (postvasectomy) and nonobstructive azoospermia – Insights from scRNA-Seq and transcriptome analysis

28 Sept 2020

Abstract excerpt

A substantial number of male infertility is caused by azoospermia. However, the underlying etiology and the molecular basis remain largely unknown. Through single-cell (sc)RNA sequencing, we had analyzed testis biopsy samples from two patients with obstructive azoospermia (OA) and nonobstructive azoospermia (NOA). We found only somatic cells in the NOA samples and explored the transcriptional changes in Sertoli...

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PMID: 35782978
DOI: 10.1016/j.gendis.2020.09.004

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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