Article
Allele-specific regulatory effects on the pig transcriptome.
GigaScience - 28 Dec 2022
Lin Yu, Li Jing, Chen Li, Bai Jingyi, Zhang Jiaman, Wang Yujie, Liu Pengliang, Long Keren, Ge Liangpeng, Jin Long, Gu Yiren, Li Mingzhou
Abstract excerpt
BACKGROUND: Allele-specific expression (ASE) refers to the preferential expression of one allele over the other and contributes to adaptive phenotypic plasticity. Here, we used a reciprocal cross-model between phenotypically divergent European Berkshire and Asian Tibetan pigs to characterize 2 ASE classes: imprinting (i.e., the unequal expression between parental alleles) and sequence dependent (i.e., unequal...
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