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Article

Novel somatic Missense Mutations in Exon 11 of the KIT Gene are Detected in Melanoma.

Asian Pacific journal of cancer prevention : APJCP - 1 Sept 2023

Palkina Nadezhda, Tyumentseva Anna, Ruksha Tatiana

Abstract excerpt

OBJECTIVE: The aim of the present study was to analyze mutations of the mast/stem cell growth factor receptor Kit (KIT) gene in patients with melanoma from Eastern Siberia regions of the Russian Federation. METHODS: KIT gene mutations in exons 11 and 13 were analyzed by Sanger sequencing in 57 tumor samples obtained from patients with KIT-positive melanomas localized in preferable locations. RESULT: Mutations...

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Identifiers

PMID: 37774052
DOI: 10.31557/APJCP.2023.24.9.3015
PMCID: PMC10762753

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