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Article

Mechanisms of PIEZO Channel Inactivation.

International journal of molecular sciences - 14 Sept 2023

Zhou Zijing, Martinac Boris

Abstract excerpt

PIEZO channels PIEZO1 and PIEZO2 are the newly identified mechanosensitive, non-selective cation channels permeable to Ca2+. In higher vertebrates, PIEZO1 is expressed ubiquitously in most tissues and cells while PIEZO2 is expressed more specifically in the peripheral sensory neurons. PIEZO channels contribute to a wide range of biological behaviors and developmental processes, therefore driving significant...

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Identifiers

PMID: 37762415
DOI: 10.3390/ijms241814113
PMCID: PMC10531961

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