Article
Circulating Tumor HPV DNA in Patients With Head and Neck Carcinoma: Correlation With HPV Genotyping.
The American journal of surgical pathology - 1 Jan 2024
Mijares Kevin, Ferrandino Rocco, Chai Raymond, Roof Scott, Bhardwaj Swati, Posner Marshall, Westra William H
Abstract excerpt
Circulating tumor human papillomavirus DNA (ctHPVDNA) testing using digital-droplet polymerase chain reaction (PCR) detects fragments of tumor-modified human papillomavirus (HPV) in the plasma of patients with HPV-associated head and neck squamous cell carcinomas (HNSCCs). Its impact on tumor surveillance and primary diagnosis is limited by unresolved issues relating to sensitivity and specificity. The study...
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