Genome-Wide Supported Risk Variants inMIR137,CACNA1C,CSMD1,DRD2, andGRM3Contribute to Schizophrenia Susceptibility in Pakistani Population

Abstract excerpt

ObjectiveaaSchizophrenia is a chronic neuropsychiatric disease afflicting around 1.1% of the population worldwide. Recently, MIR137, CACNA1C, CSMD1, DRD2, and GRM3 have been reported as the most robustly emerging candidates involved in the etiology of schizophrenia. In this case control study, we performed an association analysis of rs1625579 (MIR137), rs1006737, rs4765905 (CACNA1C), rs10503253 (CSMD1), rs1076560...