Article
Asian Zika virus can acquire generic African-lineage mutations during in utero infection.
Emerging microbes & infections - 1 Dec 2023
Sabir Ahmad Jawad, Singh Prince Pal, Trus Ivan, Le Nguyen Phuong Khanh, Karniychuk Uladzimir
Abstract excerpt
The Zika virus 2015 epidemic showed an unusual phenotype for human flaviviruses, specifically fetal infection. We previously showed that in utero inoculation with the Asian Zika virus isolated from the human sample causes persistent infection in porcine fetuses. Here, we characterized the evolution of the Asian Zika virus in the fetal brain and placenta. Interestingly, the Asian Zika virus acquired generic...
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