Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

ScRNA-seq reveals the correlation between M2 phenotype of tumor-associated macrophages and lymph node metastasis of breast cancer.

Oncology research - 1 Jan 2023

Shen Jun, Ma Hongfang, Chen Yongxia, Shen Jianguo

Abstract excerpt

The process of lymphatic metastasis was proved to be associated with podoplanin-expressing macrophages in breast cancer (BC). This study aimed to investigate the role of the M2 phenotype of tumor-associated macrophages and mine the key M2 macrophages-related genes for lymph node metastasis in BC. We downloaded the GSE158399 dataset from the Gene Expression Omnibus (GEO) database, which includes transcriptomic...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Breast Neoplasms
Share to Lymphatic Metastasis
Share to Phenotype

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Single-Cell Gene Expression Analysis

Share to Tumor-Associated Macrophages

Source

Open in PubMed Open full text

Identifiers

PMID: 37744272
DOI: 10.32604/or.2023.029638
PMCID: PMC10513958

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

ScRNA-seq reveals the correlation between M2 phenotype of tumor-associated macrophages and lymph node metastasis of breast cancer.PMID 37744272Read ↗

Integrated transcriptome and single-cell sequencing reveals M2-like tumor-associated macrophages-related prognostic signatures in breast cancerSemantic proximity Read ↗

Comprehensive multi-omics analysis identifies an immune related predicting model in early stage breast cancerSemantic proximity Read ↗

Coexpressed Genes That Promote the Infiltration of M2 Macrophages in Melanoma Can Evaluate the Prognosis and Immunotherapy OutcomeSemantic proximity Read ↗

Single-cell profiling transcriptomic reveals cellular heterogeneity and cellular crosstalk in breast cancer lymphatic node, bone, and brain metastasesSemantic proximity Read ↗

Integrated analysis of single-cell RNA-seq and bulk RNA-seq unravels the molecular feature of M2 macrophages of head and neck squamous cell carcinoma.Semantic proximity Read ↗

Metastatic breast cancers have reduced immune cell recruitment but harbor increased macrophages relative to their matched primary tumorsSemantic proximity Read ↗

Integrated transcriptional analysis reveals macrophage heterogeneity and tumor-macrophage interactions in the progression of pancreatic ductal adenocarcinomaSemantic proximity Read ↗

Bioinformatics analysis of immune infiltration patterns in breast cancer for identification of prognostic markersSemantic proximity Read ↗

Tumor-Associated Macrophage Subsets: Shaping Polarization and Targeting.Semantic proximity Read ↗

Novel Macrophage Subtype Genes for Predicting Prognosis and Immunotherapy Response in Melanoma Based on Single-Cell and Bulk RNA Sequencing AnalysisSemantic proximity Read ↗

Integrated analysis of the M2 macrophage-related signature associated with prognosis in ovarian cancerSemantic proximity Read ↗

SerpinB2 deficiency is associated with delayed mammary tumor development and decreased pro-tumorigenic macrophage polarizationSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.