Article
The genetic repertoire of deep-sea microbiome: From sequence to structure and function.
Cell host & microbe - 12 Aug 2026
Guo Yang, Wang Zongan, Li Denghui, Wang Lele, Lan Hongxia, Guo Fei, Zhao Ziyu, Liu Zhenjun, Meng Liang, Shen Xuechun, Wang Minxiao, Zhao Weishu, Zhang Weijia, Kong Chaodi, Shi Liuxin, Sun Ying, Seim Inge, Jiang Aijun, Ma Kailong, Su Zidong, Zhang Nannan, Ji Qianyue, Chen Junyi, Chen Ke, Qi Chen, Li Baitao, He Beibei, Liu Yuqian, Zhou Jiayong, Zheng Yue, Zhang Huan, Wang Yinzhao, Han Mo, Yang Tao, Tong Jiawei, Zhang Yulu, Wang Zhijie, Xu Xiaokai, Chen Jiayu, Liu Yue, Chen Haixin, Zeng Tao, Wei Xiaofeng, Li Chaolun, Yang Huanming, Wang Bo, Liu Xin, Shao Changwei, Zhang Wenwei, Gu Ying, Xiao Xiang, Xu Xun, Wang Jian, Mock Thomas, Fan Guangyi, Li Yuxiang, Liu Shanshan, Dong Yuliang
Abstract excerpt
The deep sea, as the largest and maybe most hostile environment on Earth, is still underexplored, especially regarding its genetic repertoire. Yet, previous work has revealed significant habitat-specific deep-sea biodiversity. Here, we present an integrated deep-sea microbial genetic dataset comprising 502 million nonredundant genes from 2,138 samples and 2.4 million predicted structures and use it to link...
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