Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

SARS-CoV-2 antibodies recognize 23 distinct epitopic sites on the receptor binding domain

19 Sept 2023

Abstract excerpt

The COVID-19 pandemic and SARS-CoV-2 variants have dramatically illustrated the need for a better understanding of antigen (epitope)-antibody (paratope) interactions. To gain insight into the immunogenic characteristics of epitopic sites (ES), we systematically investigated the structures of 340 Abs and 83 nanobodies (Nbs) complexed with the Receptor Binding Domain (RBD) of the SARS-CoV-2 spike protein. We...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Monoclonal and Polyclonal Antibodies Research
Share to SARS-CoV-2 and COVID-19 Research
Share to vaccines and immunoinformatics approaches

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 37726484
DOI: 10.1038/s42003-023-05332-w

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

SARS-CoV-2 antibodies recognize 23 distinct epitopic sites on the receptor binding domainPMID 37726484Read ↗

A Structural Landscape of Neutralizing Antibodies Against SARS-CoV-2 Receptor Binding DomainSemantic proximity Read ↗

N-terminal domain antigenic mapping reveals a site of vulnerability for SARS-CoV-2Semantic proximity Read ↗

Structural and energetic profiling of SARS-CoV-2 receptor binding domain antibody recognition and the impact of circulating variantsSemantic proximity Read ↗

The antigenic anatomy of SARS-CoV-2 receptor binding domainSemantic proximity Read ↗

Exploring B-cell epitope conservation and antigenicity shift in current COVID-19 variants: Analyzing spike-antibody interactions for therapeutic uses.Semantic proximity Read ↗

Omicron-specific ultra-potent SARS-CoV-2 neutralizing antibodies targeting the N1/N2 loop of Spike N-terminal domainSemantic proximity Read ↗

N-terminal domain antigenic mapping reveals a site of vulnerability for SARS-CoV-2.Semantic proximity Read ↗

SARS-CoV-2 Omicron (BA.1 and BA.2) specific novel CD8+ and CD4+ T cell epitopes targeting spike proteinSemantic proximity Read ↗

The landscape of antibody binding in SARS-CoV-2 infectionSemantic proximity Read ↗

Antibody accessibility determines location of spike surface mutations in SARS-CoV-2 variants.Semantic proximity Read ↗

Comprehensive structural analysis reveals broad-spectrum neutralizing antibodies against SARS-CoV-2 Omicron variantsSemantic proximity Read ↗

MHC-II constrains the natural neutralizing antibody response to the SARS-CoV-2 spike RBM in humansSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.