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Programmed Cell Death in Unicellular Versus Multicellular Organisms

19 Sept 2023

Abstract excerpt

Programmed cell death (self-induced) is intrinsic to all cellular life forms, including unicellular organisms. However, cell death research has focused on animal models to understand cancer, degenerative disorders, and developmental processes. Recently delineated suicidal death mechanisms in bacteria and fungi have revealed ancient origins of animal cell death that are intertwined with immune mechanisms, allaying...

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PMID: 37722687
DOI: 10.1146/annurev-genet-033123-095833

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