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Article

Association between single nucleotide polymorphism of DNA damage repair related genes and radiosensitivity in healthy individuals.

Radiation protection dosimetry - 18 Sept 2023

Yuan Yayi, Liu Xiaoming, Dong Yuyang, Zhang Ruifeng, Meng Qianqian, Dang Xuhong, Li Lin, Ren Yue, Dong Juancong

Abstract excerpt

Radiosensitivity in humans can influence radiation-induced normal tissue toxicity. As radiosensitivity has a genetic predisposition, we aimed to investigate the possible association between four single nucleotide polymorphism (SNP) sites and the radiosensitivity in healthy people. We genotyped four selected SNPs: TRIP12 (rs13018957), UIMC1 (rs1700490) and POLN (rs2022302), and analyzed the association between SNP...

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PMID: 37721085
DOI: 10.1093/rpd/ncad204

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