Article
Dysregulation of MicroRNAs in Adult Osteogenesis Imperfecta: The miROI Study.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research - 1 Nov 2023
Mercier-Guery Alexandre, Millet Marjorie, Merle Blandine, Collet Corinne, Bagouet Flora, Borel Olivier, Sornay-Rendu Elisabeth, Szulc Pawel, Vignot Emmanuelle, Gensburger Deborah, Fontanges Elisabeth, Croset Martine, Chapurlat Roland
Abstract excerpt
As epigenetic regulators of gene expression, circulating micro-RiboNucleic Acids (miRNAs) have been described in several bone diseases as potential prognostic markers. The aim of our study was to identify circulating miRNAs potentially associated with the severity of osteogenesis imperfecta (OI) in three steps. We have screened by RNA sequencing for the miRNAs that were differentially expressed in sera of a small...
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