Article
Biomarkers in bipolar disorder: a positional paper from the International Society for Bipolar Disorders Biomarkers Task Force.
The Australian and New Zealand journal of psychiatry - 1 Apr 2013
Frey Benicio N, Andreazza Ana C, Houenou Josselin, Jamain Stéphane, Goldstein Benjamin I, Frye Mark A, Leboyer Marion, Berk Michael, Malhi Gin S, Lopez-Jaramillo Carlos, Taylor Valerie H, Dodd Seetal, Frangou Sophia, Hall Geoffrey B, Fernandes Brisa S, Kauer-Sant'Anna Marcia, Yatham Lakshmi N, Kapczinski Flavio, Young L Trevor
Abstract excerpt
Although the etiology of bipolar disorder remains uncertain, multiple studies examining neuroimaging, peripheral markers and genetics have provided important insights into the pathophysiologic processes underlying bipolar disorder. Neuroimaging studies have consistently demonstrated loss of gray matter, as well as altered activation of subcortical, anterior temporal and ventral prefrontal regions in response to...
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