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Tenofovir diphosphate in dried blood spots and HIV-1 resistance in South Africa

14 Sept 2023

Abstract excerpt

BACKGROUND: Suboptimal antiretroviral (ART) adherence can lead to virologic failure with consequent HIV-1 resistance. Tenofovir diphosphate (TFV-DP) in dried blood spots (DBS) is a powerful biomarker of cumulative adherence, predictive of future viremia. It has been associated with resistance in Persons With HIV (PWH) in South Africa and the US. We explored the relationship of TFV-DP concentrations with...

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PMID: 37705102
DOI: 10.1186/s12981-023-00552-w

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