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The clusterin connectome: Emerging players in chondrocyte biology and putative exploratory biomarkers of osteoarthritis

15 Mar 2023

Abstract excerpt

Introduction: Clusterin is a moonlighting protein that has many functions. It is a multifunctional holdase chaperone glycoprotein that is present intracellularly and extracellularly in almost all bodily fluids. Clusterin is involved in lipid transport, cell differentiation, regulation of apoptosis, and clearance of cellular debris, and plays a protective role in ensuring cellular survival. However, the possible...

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PMID: 37033956
DOI: 10.3389/fimmu.2023.1103097

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