Article
Mutational landscape and predictors of survival in head and neck mucosal melanoma.
International forum of allergy & rhinology - 1 Apr 2024
Lehrich Brandon M, Abiri Arash, Nguyen Theodore V, Bitner Benjamin F, Tong Charles C L, Kuan Edward C
Abstract excerpt
KEY POINTS: Head and neck mucosal melanomas have a diverse mutational landscape with low mutational burden. A molecular subset (∼13%) has ROS1 mutations, which is an actionable driver mutation. ROS1-mutated patients have improved overall survival likely due to high mutational burden.
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