Article
Characterization of genetics in patients with mucosal melanoma treated with immune checkpoint blockade.
Cancer medicine - 1 Apr 2021
Buchbinder Elizabeth I, Weirather Jason L, Manos Michael, Quattrochi Brian J, Sholl Lynette M, Brennick Ryan C, Bowling Peter, Bailey Nancy, Magarace Lisa, Ott Patrick A, Haq Rizwan, Izar Benjamin, Giobbie-Hurder Anita, Hodi F Stephen
Abstract excerpt
Mucosal melanoma is a rare form of melanoma which arises from melanocytes in the mucosal membranes and can be effectively treated with immune checkpoint blockade (ICB). However, response rates in mucosal melanoma are lower than those observed for cutaneous melanomas. Targeted sequencing of up to 447 genes (OncoPanel) was performed on tumors from all mucosal melanoma patients seen at the Dana-Farber Cancer...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
