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Article

Influenza virus transcription and progeny production are poorly correlated in single cells.

eLife - 7 Sept 2023

Bacsik David J, Dadonaite Bernadeta, Butler Andrew, Greaney Allison J, Heaton Nicholas S, Bloom Jesse D

Abstract excerpt

The ultimate success of a viral infection at the cellular level is determined by the number of progeny virions produced. However, most single-cell studies of infection quantify the expression of viral transcripts and proteins, rather than the amount of progeny virions released from infected cells. Here, we overcome this limitation by simultaneously measuring transcription and progeny production from single...

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Identifiers

PMID: 37675839
DOI: 10.7554/eLife.86852
PMCID: PMC10484525

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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