Article
Automated machine learning for genome wide association studies.
Bioinformatics (Oxford, England) - 2 Sept 2023
Lakiotaki Kleanthi, Papadovasilakis Zaharias, Lagani Vincenzo, Fafalios Stefanos, Charonyktakis Paulos, Tsagris Michail, Tsamardinos Ioannis
Abstract excerpt
MOTIVATION: Genome-wide association studies (GWAS) present several computational and statistical challenges for their data analysis, including knowledge discovery, interpretability, and translation to clinical practice. RESULTS: We develop, apply, and comparatively evaluate an automated machine learning (AutoML) approach, customized for genomic data that delivers reliable predictive and diagnostic models, the set...
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