Article
Interaction of multidrug-resistant hypervirulent Klebsiella pneumoniae with components of human innate host defense.
mBio - 31 Oct 2023
DeLeo Frank R, Porter Adeline R, Kobayashi Scott D, Freedman Brett, Hao Mingju, Jiang Jianping, Lin Yi-Tsung, Kreiswirth Barry N, Chen Liang
Abstract excerpt
IMPORTANCE: Klebsiella pneumoniae strains with a combination of multidrug resistance and hypervirulence genotypes (MDR hvKp) have emerged as a cause of human infections. The ability of these microbes to avoid killing by the innate immune system remains to be tested fully. To that end, we compared the ability of a global collection of hvKp and MDR hvKp clinical isolates to survive in human blood and resist...
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