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Article

Omics-driven investigation of the biology underlying intrinsic submaximal working capacity and its trainability.

Physiological genomics - 1 Nov 2023

Hota Monalisa, Barber Jacob L, Ruiz-Ramie Jonathan J, Schwartz Charles S, Lam Do Thuy Uyen Ha, Rao Prashant, Mi Michael Y, Katz Daniel H, Robbins Jeremy M, Clish Clary B, Gerszten Robert E, Sarzynski Mark A, Ghosh Sujoy, Bouchard Claude

Abstract excerpt

Submaximal exercise capacity is an indicator of cardiorespiratory fitness with clinical and public health implications. Submaximal exercise capacity and its response to exercise programs are characterized by heritability levels of about 40%. Using physical working capacity (power output) at a heart rate of 150 beats/min (PWC150) as an indicator of submaximal exercise capacity in subjects of the HERITAGE Family...

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Identifiers

PMID: 37661925
DOI: 10.1152/physiolgenomics.00163.2022
PMCID: PMC11178266

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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