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Identification of molecular subtyping system and four-gene prognostic signature with immune-related genes for uveal melanoma.

Experimental biology and medicine (Maywood, N.J.) - 1 Feb 2022

Xia Fei, Yu Zhilong, Deng Aijun, Gao Guohong

Abstract excerpt

Immunotherapy is the most promising treatment for uveal melanoma patients with metastasis. Tumor microenvironment plays an essential role in tumor progression and greatly affects the efficacy of immunotherapy. This research constructed an immune-related subtyping system and discovered immune prognostic genes to further understand the immune mechanism in uveal melanoma. Immune-related genes were determined from...

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Immunotherapy
Interferon Regulatory Factor-1
Interleukins
Proto-Oncogene Proteins c-vav
Sorting Nexins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Tumor Microenvironment

Uveal Neoplasms

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PMID: 34743576
DOI: 10.1177/15353702211053801
PMCID: PMC8851532

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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