Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Therapeutically useful mycobacteriophages BPs and Muddy require trehalose polyphleates

24 Aug 2023

Abstract excerpt

Mycobacteriophages show promise as therapeutic agents for non-tuberculous mycobacterium infections. However, little is known about phage recognition of Mycobacterium cell surfaces or mechanisms of phage resistance. We show here that trehalose polyphleates (TPPs)-high-molecular-weight, surface-exposed glycolipids found in some mycobacterial species-are required for infection of Mycobacterium abscessus and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bacteriophages and microbial interactions
Share to Microbial infections and disease research
Share to Mycobacterium research and diagnosis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 37644325
DOI: 10.1038/s41564-023-01451-6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Therapeutically useful mycobacteriophages BPs and Muddy require trehalose polyphleatesPMID 37644325Read ↗

Trehalose polyphleates participate in Mycobacterium abscessus fitness and pathogenesisSemantic proximity Read ↗

Lipid metabolic pathways determine phage infectivity in <i>Mycobacterium abscessus</i>Semantic proximity Read ↗

Phage Therapy for Nontuberculous Mycobacteria: Challenges and OpportunitiesSemantic proximity Read ↗

Smooth-to-rough morphotype switching, a mechanism of phage resistance in Mycobacterium abscessus.Semantic proximity Read ↗

Mycobacteriophage TM4 requires XylR for successful infection in <i>Mycobacterium smegmatis</i> mc <sup>2</sup> 155Semantic proximity Read ↗

Underestimated Manipulative Roles of Mycobacterium tuberculosis Cell Envelope Glycolipids During InfectionSemantic proximity Read ↗

High-density transposon mutagenesis in <i>Mycobacterium abscessus</i> identifies an essential penicillin-binding lipo-protein (PBP-lipo) involved in septal peptidoglycan synthesis and antibiotic sensitivitySemantic proximity Read ↗

Mycobacteriophages and Their ApplicationsSemantic proximity Read ↗

Transposon mutagenesis in Mycobacterium abscessus identifies an essential penicillin-binding protein involved in septal peptidoglycan synthesis and antibiotic sensitivitySemantic proximity Read ↗

Phage Therapy for Mycobacterium Abscessus and Strategies to Improve OutcomesSemantic proximity Read ↗

Targeting trehalose and methylglucose lipopolysaccharide biosynthetic pathways in M. tuberculosis : structural and functional characterisation, and early-stage drug discovery of OtsA and Rv3030Semantic proximity Read ↗

Understanding the Phage–Host Interaction Mechanism toward Improving the Efficacy of Current Antibiotics in Mycobacterium abscessusSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.