Article
Clinical and genetic analysis of essential hypertension with CYB gene m.15024G>A mutation.
Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences - 25 Aug 2023
He Yunfan, Li Wenxu, Liu Zhen, Zhang Juanjuan, Guan Minxin
Abstract excerpt
OBJECTIVES: To explore the role of mitochondrial CYB 15024G>A mutation in the development of essential hypertension. METHODS: Mitochondrial genome sequences of hypertensive patients were obtained from previous studies. Clinical and genetic data of a hypertensive patient with mitochondrial CYB 15024G>A mutation and its pedigree were analyzed. Lymphocytes derived from patient and family members were transformed...
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