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Article

Presence of mutation m.14484T>C in a Chinese family with maternally inherited essential hypertension but no expression of LHON.

Biochimica et biophysica acta - 1 Oct 2012

Guo Hao, Zhuang Xin-Ying, Zhang A-Mei, Zhang Wen, Yuan Yong, Guo Li, Yu Dandan, Liu Juan, Yang Da-Kuan, Yao Yong-Gang

Abstract excerpt

Essential hypertension (EH, MIM 145500) is the most common cardiovascular disease and affects one-quarter of the world's adult population. Families with EH in a mode of maternal transmission have been occasionally observed in clinical settings and suggested an involvement of mitochondrial DNA (mtDNA) mutation. We aimed to characterize the role of mtDNA mutation in EH. We reported a large Han Chinese family with a...

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Identifiers

PMID: 22749828
DOI: 10.1016/j.bbadis.2012.06.010

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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