Different Genetic Signatures of Small‐Cell Lung Cancer Characterize Anti‐GABA B R and Anti‐Hu Paraneoplastic Neurological Syndromes

Abstract excerpt

Objective Small‐cell lung cancer (SCLC) is the malignancy most frequently associated with paraneoplastic neurological syndromes (PNS) and can trigger different antibody responses against intracellular (Hu) or neuronal surface (GABA B R) antigens. Our aim was to clarify whether the genomic and transcriptomic features of SCLC are different in patients with anti‐GABA B R or anti‐Hu PNS compared with SCLC without...

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