Article
Genomic analysis defines distinct pancreatic and neuronal subtypes of lung carcinoid.
The Journal of pathology - 1 Nov 2024
Domingo-Sabugo Clara, Willis-Owen Saffron Ag, Mandal Amit, Nastase Anca, Dwyer Sarah, Brambilla Cecilia, Gálvez José Héctor, Zhuang Qinwei, Popat Sanjay, Eveleigh Robert, Munter Markus, Lim Eric, Nicholson Andrew G, Lathrop G Mark, Cookson William Oc, Moffatt Miriam F
Abstract excerpt
Lung carcinoids (L-CDs) are rare, poorly characterised neuroendocrine tumours (NETs). L-CDs are more common in women and are not the consequence of cigarette smoking. They are classified histologically as typical carcinoids (TCs) or atypical carcinoids (ACs). ACs confer a worse survival. Histological classification is imperfect, and there is increasing interest in molecular markers. We therefore investigated...
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