Haplotype based testing for a better understanding of the selective architecture.

Abstract excerpt

BACKGROUND: The identification of genomic regions affected by selection is one of the most important goals in population genetics. If temporal data are available, allele frequency changes at SNP positions are often used for this purpose. Here we provide a new testing approach that uses haplotype frequencies instead of allele frequencies. RESULTS: Using simulated data, we show that compared to SNP based test, our...

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