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Article

PIEZO2 and perineal mechanosensation are essential for sexual function

24 Aug 2023

Abstract excerpt

Despite the potential importance of genital mechanosensation for sexual reproduction, little is known about how perineal touch influences mating. We explored how mechanosensation affords exquisite awareness of the genitals and controls reproduction in mice and humans. Using genetic strategies and in vivo functional imaging, we demonstrated that the mechanosensitive ion channel PIEZO2 (piezo-type mechanosensitive...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 37616369
DOI: 10.1126/science.adg0144

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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