Article
crosshap: R package for local haplotype visualization for trait association analysis.
Bioinformatics (Oxford, England) - 1 Aug 2023
Marsh Jacob I, Petereit Jakob, Johnston Brady A, Bayer Philipp E, Tay Fernandez Cassandria G, Al-Mamun Hawlader A, Batley Jacqueline, Edwards David
Abstract excerpt
SUMMARY: Genome-wide association studies (GWAS) excels at harnessing dense genomic variant datasets to identify candidate regions responsible for producing a given phenotype. However, GWAS and traditional fine-mapping methods do not provide insight into the complex local landscape of linkage that contains and has been shaped by the causal variant(s). Here, we present crosshap, an R package that performs robust...
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