Article
PheGWAS: a new dimension to visualize GWAS across multiple phenotypes.
Bioinformatics (Oxford, England) - 15 Apr 2020
George Gittu, Gan Sushrima, Huang Yu, Appleby Philip, Nar A S, Venkatesan Radha, Mohan Viswanathan, Palmer Colin N A, Doney Alex S F
Abstract excerpt
MOTIVATION: PheGWAS was developed to enhance exploration of phenome-wide pleiotropy at the genome-wide level through the efficient generation of a dynamic visualization combining Manhattan plots from GWAS with PheWAS to create a 3D 'landscape'. Pleiotropy in sub-surface GWAS significance strata can be explored in a sectional view plotted within user defined levels. Further complexity reduction is achieved by...
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