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Article

Novel linkage and association of TCF7L2 variants with PCOS in Italian families.

European review for medical and pharmacological sciences - 1 Aug 2023

Amin M, Del Bosque-Plata L, Gragnoli C

Abstract excerpt

OBJECTIVE: Transcription factor 7-like 2 (TCF7L2) gene variants confer risk for type 2 diabetes and metabolic traits. We investigated the role of TCF7L2-variants in polycystic ovarian syndrome (PCOS), which is a common endocrine metabolic disorder affecting women of reproductive age. We tested whether TCF7L2 variants are in linkage to and/or in linkage disequilibrium [(LD), namely linkage and association)] with...

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Identifiers

PMID: 37606143
DOI: 10.26355/eurrev_202308_33306

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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