Article
Detection of single nucleotide polymorphisms in virus genomes assembled from high-throughput sequencing data: large-scale performance testing of sequence analysis strategies.
PeerJ - 1 Jan 2023
Rollin Johan, Bester Rachelle, Brostaux Yves, Caglayan Kadriye, De Jonghe Kris, Eichmeier Ales, Foucart Yoika, Haegeman Annelies, Koloniuk Igor, Kominek Petr, Maree Hans, Onder Serkan, Posada Céspedes Susana, Roumi Vahid, Šafářová Dana, Schumpp Olivier, Ulubas Serce Cigdem, Sõmera Merike, Tamisier Lucie, Vainio Eeva, van der Vlugt Rene Aa, Massart Sebastien
Abstract excerpt
Recent developments in high-throughput sequencing (HTS) technologies and bioinformatics have drastically changed research in virology, especially for virus discovery. Indeed, proper monitoring of the viral population requires information on the different isolates circulating in the studied area. For this purpose, HTS has greatly facilitated the sequencing of new genomes of detected viruses and their comparison....
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