Article
Noninvasive prenatal screening in twin pregnancies with cell-free DNA using the IONA test: a prospective multicenter study
15 Jan 2021
Abstract excerpt
BACKGROUND: In singleton pregnancies, studies investigating cell-free DNA in maternal blood have consistently reported high detection rate and low false-positive rate for the 3 common fetal trisomies (trisomies 21, 18, and 13). The potential advantages of noninvasive prenatal testing in twin pregnancies are even greater than in singletons, in particular lower need for invasive testing and consequent fetal loss...
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