Article
Detection of triploid, molar, and vanishing twin pregnancies by a single-nucleotide polymorphism-based noninvasive prenatal test.
American journal of obstetrics and gynecology - 1 Jan 2015
Curnow Kirsten J, Wilkins-Haug Louise, Ryan Allison, Kırkızlar Eser, Stosic Melissa, Hall Megan P, Sigurjonsson Styrmir, Demko Zachary, Rabinowitz Matthew, Gross Susan J
Abstract excerpt
OBJECTIVE: We sought to determine the ability of single-nucleotide polymorphism-based noninvasive prenatal testing (NIPT) to identify triploid, unrecognized twin, and vanishing twin pregnancies. STUDY DESIGN: The study included 30,795 consecutive reported clinical cases received for NIPT for fetal whole-chromosome aneuploidies; known multiple gestations were excluded. Cell-free DNA was isolated from maternal...
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