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Article

NEK8 regulates colorectal cancer progression via phosphorylating MYC

18 Aug 2023

Abstract excerpt

Radiotherapy and chemotherapy remain the mainstay of treatment for colorectal cancer (CRC), although their efficacy is limited. A detailed understanding of the molecular mechanisms underlying CRC progression could lead to the development of new therapeutic strategies. Although it has been established that MYC signaling is dysregulated in various human cancers, direct targeting MYC remains challenging due to its...

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PMID: 37596667
DOI: 10.1186/s12964-023-01215-z

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