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Role of CELF2 in ferroptosis: Potential targets for cancer therapy (Review)

9 Aug 2023

Abstract excerpt

Ferroptosis is a novel form of regulated cellular necrosis that plays a critical role in promoting cancer progression and developing drug resistance. The main characteristic of ferroptosis is iron‑dependent lipid peroxidation caused by excess intracellular levels of reactive oxygen species. CUGBP ELAV‑like family number 2 (CELF2) is an RNA‑binding protein that is downregulated in various types of cancer and is...

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PMID: 37594127
DOI: 10.3892/ijmm.2023.5291

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