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TP53 alterations of hormone-naïve prostate cancer in the Chinese population.

Prostate cancer and prostatic diseases - 1 Jun 2021

Liu Zhengfang, Guo Hu, Zhu Yaofeng, Xia Yangyang, Cui Jianfeng, Shi Kai, Fan Yidong, Shi Benkang, Chen Shouzhen

Abstract excerpt

BACKGROUND: Prostate cancer (PCa) shows racial disparity in clinical and genomic characteristics, and Asian patients with PCa often present with more aggressive phenotypes at diagnosis. The ability of TP53 to serve as a prognostic biomarker of PCa has been well studied in Western populations. However, no studies to date have examined the role of TP53 in the disparities of primary hormone-naïve prostate cancer...

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Source

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Identifiers

PMID: 33214693
DOI: 10.1038/s41391-020-00302-3
PMCID: PMC8134057

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