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Comparison of genome replication fidelity between SARS-CoV-2 and influenza A virus in cell culture

11 Aug 2023

Abstract excerpt

Abstract Since the emergence of COVID-19, several SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2) variants have emerged and spread widely. These variants are produced through replication errors of the viral genome by viral RNA-dependent RNA polymerase (RdRp). Seasonal epidemics of influenza are also known to occur because of new variants of influenza A virus (IAV), which are generated by the...

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PMID: 37567927
DOI: 10.1038/s41598-023-40463-4

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