Article
Correlation of polymerase replication fidelity with genetic evolution of influenza A/Fujian/411/02(H3N2) viruses.
Journal of medical virology - 1 Mar 2011
Wong Karen Ka Yin, Bull Rowena A, Rockman Steve, Scott Gillian, Stelzer-Braid Sacha, Rawlinson William
Abstract excerpt
Influenza virus evolves continuously through mutations presumed to result from evolutionary pressure driving viral replication. This study examined the relationship between the genetic evolution and replication fidelity of influenza viruses. Analysis of influenza sequences from National Centre for Biotechnology Information (NCBI) database revealed a gradual decrease in the rate of genetic evolution of...
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