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Article

Maast: genotyping thousands of microbial strains efficiently.

Genome biology - 10 Aug 2023

Shi Zhou Jason, Nayfach Stephen, Pollard Katherine S

Abstract excerpt

Existing single nucleotide polymorphism (SNP) genotyping algorithms do not scale for species with thousands of sequenced strains, nor do they account for conspecific redundancy. Here we present a bioinformatics tool, Maast, which empowers population genetic meta-analysis of microbes at an unrivaled scale. Maast implements a novel algorithm to heuristically identify a minimal set of diverse conspecific genomes,...

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Identifiers

PMID: 37563669
DOI: 10.1186/s13059-023-03030-8
PMCID: PMC10416524

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

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