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Article

BMP9 maintains the phenotype of HTR-8/Svneo trophoblast cells by activating the SDF1/CXCR4 pathway.

BMC molecular and cell biology - 7 Aug 2023

Yang Xue, Ren Lingling, Chen Xiang, Pang Ying, Jia Baoxia, Sun Jing, Quan Xiaofang

Abstract excerpt

BACKGROUND: Bone morphogenetic protein 9 (BMP9) has been shown to regulate processes such as angiogenesis, endothelial dysfunction, and tumorigenesis. However, the role of BMP9 in preeclampsia (PE) is unclear. The purpose of this study was to investigate the role and mechanism of BMP9 in PE. METHODS: The effects of BMP9 on the viability, migration and invasion of HTR-8/Svneo cells were investigated by CCK-8...

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Identifiers

PMID: 37550619
DOI: 10.1186/s12860-023-00487-0
PMCID: PMC10405378

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