Article
Untargeted metabolomics and phenotype data indicate the therapeutic and prophylactic potential of Lysimachia candida Lindl. towards high-fat high-fructose-induced metabolic syndrome in rats.
Molecular omics - 4 Dec 2023
Alam Md Jahangir, Kamboj Parul, Sarkar Soumalya, Gupta Sonu Kumar, Kasarla Siva Swapna, Bajpai Sneh, Kumari Deepika, Bisht Neema, Barge Sagar Ramrao, Kashyap Bhaswati, Deka Barsha, Bharadwaj Simanta, Rahman Seydur, Dutta Partha Pratim, Borah Jagat C, Talukdar Narayan Chandra, Kumar Yashwant, Banerjee Sanjay K
Abstract excerpt
The present study evaluated the therapeutic potential of the medicinal plant Lysimachia candida Lindl. against metabolic syndrome in male SD rats fed with a high-fat high-fructose (HFHF) diet. Methanolic extract of Lysimachia candida Lindl. (250 mg kg-1 body weight p.o.) was administrated to the HFHF-fed rats daily for 20 weeks. Blood samples were collected, and blood glucose levels and relevant biochemical...
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